I'm having this same problem with ProSim737. I've been searching for a fix but so far no luck. I removed all of my simconnect entries, ran a repair on P3D V5 and went into v5 redist folder to add the simconnect versions in. Testing that now. If you find a fix Giuseppe please add it in to this thread. If I can't solve it I'll probably send in a ticket to ProSim once i've exhausted all my ideas. The following gives me some impression it is SimConnect.
4/15/2020 2:48:05 PM * SimConnect:Lockheed Martin® Prepar3D® v5 Version 5.0.21.34709 - SimConnect Version 5.0.0.0
4/15/2020 2:48:05 PM * SimConnect:ProSim P3DV4 Module detected: 103
4/15/2020 2:48:05 PM * Simconnect:Exception: ILLEGAL_OPERATION, index: 4294967295
4/15/2020 2:53:14 PM * VersionManager:Failed to install version 1.30. The request was aborted: Could not create SSL/TLS secure channel. -- Url: https://cdndl.prosim-ar.com/api/dl
4/15/2020 4:22:29 PM SimConnect: SimStop
4/15/2020 4:22:34 PM FSUIPCConnection: 5670.42 2002.47 SendMessageAsync: TryRemove
4/15/2020 4:22:36 PM FSUIPCConnection: 5672.53 1999.50 SendMessageAsync: TryRemove
4/15/2020 4:22:39 PM * Simconnect init:Exception:The operation has timed out.
Update: Refreshing simconnect did not do the trick.
Chris Meyer