hi Pete thanks for the reply 
i downloaded FSUIPC 3.65, still having the same probleme with PMDG  
the auto brakes does not work. the same setting are working nicely with level-D and other A/C. 
for the brakes message it works with auto brakes. 
regarding the calibration what is the best way to do it? 
i tryed this: 
[Axes.Emirates Sky Cargo - 747-400F GE CF6 Engines] 
0=1X,256,D,7,0,0,0 
1=1X,D,-16200,-6200,1070,190 
2=1Y,256,D,8,0,0,0 
3=1Y,D,-16200,-6200,1070,190 
4=1Z,256,D,3,0,0,0 
5=2X,256,D,1,0,0,0 
6=2Y,256,D,2,0,0,0 
7=3X,256,D,22,0,0,0 
8=3X,D,6000,8000,1070,191 
9=3R,256,D,23,0,0,0 
[JoystickCalibration.Emirates Sky Cargo - 747-400F GE CF6 Engines] 
ExclThrottleSet=No 
SepRevsJetsOnly=No 
ApplyHeloTrim=No 
FlapsSetControl=0 
FlapDetents=No 
ReverserControl=66292 
Reverser1Control=66422 
Reverser2Control=66425 
Reverser3Control=66428 
Reverser4Control=66431 
MaxThrottleForReverser=256 
AileronTrimControl=0 
RudderTrimControl=0 
CowlFlaps1Control=0 
CowlFlaps2Control=0 
CowlFlaps3Control=0 
CowlFlaps4Control=0 
Aileron=-15000,-512,512,15000/8 
Elevator=-15000,-512,512,15000/8 
Rudder=-15000,-512,512,15000/8 
Spoilers=-16200,16200/24 
Flaps=-16200,16200/24 
LeftBrake=-16380,16380/24 
RightBrake=-16380,16380/24 
MaxSteerSpeed=60 
SlopeLeftBrake=10 
SlopeRightBrake=10 
SlopeRudder=2 
SlopeAileron=2 
SlopeElevator=2 
[Axes.Level D Simulations B767-300ER] 
0=1X,256,D,7,0,0,0 
1=1X,D,-16200,-6200,1070,190 
2=1Y,256,D,8,0,0,0 
3=1Y,D,-16200,-6200,1070,190 
4=1Z,256,D,3,0,0,0 
5=2X,256,D,1,0,0,0 
6=2Y,256,D,2,0,0,0 
7=3X,256,D,22,0,0,0 
8=3X,D,6000,8000,1070,191 
9=3R,256,D,23,0,0,0 
[JoystickCalibration.Level D Simulations B767-300ER] 
ExclThrottleSet=No 
SepRevsJetsOnly=No 
ApplyHeloTrim=No 
FlapsSetControl=0 
FlapDetents=No 
ReverserControl=66292 
Reverser1Control=66422 
Reverser2Control=66425 
Reverser3Control=66428 
Reverser4Control=66431 
MaxThrottleForReverser=256 
AileronTrimControl=0 
RudderTrimControl=0 
CowlFlaps1Control=0 
CowlFlaps2Control=0 
CowlFlaps3Control=0 
CowlFlaps4Control=0 
Aileron=-15000,-512,512,15000/8 
Elevator=-15000,-512,512,15000/8 
Rudder=-15000,-512,512,15000/8 
Spoilers=-16200,16200/24 
Flaps=-16200,16200/24 
LeftBrake=-16200,16200/24 
RightBrake=-16200,16200/24 
MaxSteerSpeed=60 
SlopeRudder=5 
SlopeAileron=10 
SlopeElevator=5 
SlopeLeftBrake=10 
SlopeRightBrake=10