As a recent newcomer to the E170 aircraft, I have just come across the same issue. I was actually doing a tutorial flight, step by step from a published tutorial. As Tony had said, all the data had been wiped from the FMC after entering arrival information. In my case, the aircraft continued following the flight plan but shortly after losing all the data from the FMC, FSX crashed with the following error message.
Problem signature:
Problem Event Name: BEX
Application Name: fsx.exe
Application Version: 10.0.61637.0
Application Timestamp: 46fadb14
Fault Module Name: EJet.GAU
Fault Module Version: 1.0.0.1
Fault Module Timestamp: 48c914de
Exception Offset: 00137ecc
Exception Code: c000000d
Exception Data: 00000000
OS Version: 6.1.7601.2.1.0.256.48
Locale ID: 1033
Additional Information 1: f277
Additional Information 2: f277bfa2566bec97fe01dd51ab401ba8
Additional Information 3: c734
Additional Information 4: c734cfcd72ee94b640e8eff10d2d24a4
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I installed the E170 on July 28th and only today set up a full flight.